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    《2007AUA臨床局限性前列腺癌指南》內(nèi)容簡(jiǎn)介：

    In December 1995, the American Urological Association (AUA) published the Report on theManagement of Clinically Localized Prostate Cancer.1The document was the culmination of sixyears of work by 17 clinicians and scientists and required the evaluation of 12,501 scientificpublications with the detailed extraction of ***rmation from 165 papers that met the rigorouscriteria of the panel of experts (Appendix 1). The Panel noted that a lack of evidence precludedspecific recommendations for optimal treatment of an individual patient, which patients shouldbe offered all treatment options, and that patient preferences should guide decision making.

    《2007AUA臨床局限性前列腺癌指南》內(nèi)容預(yù)覽：

    Since 1995, approximately 2,600,000 men2in the United States have been diagnosed withprostate cancer, and nearly 375,000 men3, 4have lost their lives to this disease. In addition, theNational Cancer Institute4has spent $2.1 billion on prostate cancer research and as of November2005, approximately 28,111 scientific papers concerning prostate cancer have been published inpeer-reviewed medical journals (OVID Search, December 31, 1995 to October 23, 2005; keyword: prostatic neoplasms). At the same time, mortality rates from prostate cancer have beendeclining: 34,475 men died in 1995 compared with an estimated 30,350 in 2005.4Severalpivotal randomized clinical trials related to prostate cancer treatment have been completed,including a chemoprevention study,5along with studies demonstrating prolongation of life inmen with hormone-refractory metastatic disease6, 7and improved outcomes in men withnonmetastatic disease.8-35With the use of new and combined treatments, the frequency andvariety of complications have differed from those previously reported. Advances have beenmade in prostate cancer imaging, biopsy methodology, in understanding causative factors anddisease, in treatment-related quality of life and in predicting the behavior of individual tumorsusing risk strata.

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